Thursday, October 31, 2019
Research Critical Appraisal Article Paper Example | Topics and Well Written Essays - 750 words
Critical Appraisal Article - Research Paper Example Need for urgent treatment and trauma undermine initiatives for preserving fertility and little knowledge exists on perception of the patients and their decisions on fertility preservation following availed information. The clinical problem was therefore preservation of fertility among cancer patients, who are still in their reproductive age, prior to treatment. The research problem however, was lack of knowledge on perception of cancer among patients of the reproductive age, based on availed information, and use of fertility preservation techniques. This knowledge, among care providers and patients, can inform decisions on preservation of fertility (Peddie, Porter, Barbour, Culligan, MacDonald, King, Horn, and Bhattacharya, 2012). The author established significance of the study through identifying the target population, significance of reproduction to the population, and threat to reproduction due to uninformed decisions into cancer treatment, following diagnosis. Importance of reproduction to the society identifies significance of the problem to every individual who has understood the role of procreation and wish for personal fertility of that of a friend, relative, or an associate. Identification of existence of fertility preservation techniques that were still underutilized also established significance of the study to diagnosed cancer patients and those who have not been diagnosed with cancer because everyone is at risk. The purpose of the study was to expand the audienceââ¬â¢s knowledge on factors that influence peopleââ¬â¢s decisions to preserve their fertility following cancer diagnosis and current application of available fertility preservation methods. The study aimed at developing knowledge on patientsââ¬â¢ perception on and use of fertility preservation method and these relate to the research problem of lack of knowledge on patientsââ¬â¢ perception on and application of the preservation techniques. The objective
Tuesday, October 29, 2019
Ppt Financial Derivatives Essay Example for Free
Ppt Financial Derivatives Essay GLOBAL EDITION MULTINATIONAL BUSINESS FINANCE 12TH EDITION David K. Arthur I. Michael H. EITEMAN University of California, Los Angeles STONEHILL Oregon State University and the University of Hawaii at Manoa MOFFETT Thunderbird School of Global Management Boston Columbus Indianapolis New York San Francisco Upper Saddle River Amsterdam Cape Town Dubai London Madrid Milan Munich Paris Montreal Toronto Delhi Mexico City Sao Paulo Sydney Hong Kong Seoul Singapore Taipei Tokyo Contents PART I G l o b a l Financial E n v i r o n m e n t 1 Chapter 1 Globalization and the MyBtiBnatiomaO Enterprise 2 Globalization and Creating Value in the Multinational Enterprise 3 The Theory of Comparative Advantage 4 What Is Different about Global Financial Management? 7 Market Imperfections: A Rationale for the Existence of the Multinational Firm 8 The Globalization Process 9 Summary Points 13 MINI-CASE: Porsche Changes Tack 13 Questions â⬠¢ Problems â⬠¢ Internet Exercises 19 Chapter 2 Financial Goals and Corporate Governance Who Owns the Business? 22 What Is the Goal of Management? 24 Corporate Governance 28 Summary Points 40 MINI-CASE: Governance Failure at Enron 41 Questions n Problems n Internet Exercises 45 22 Chapter 3 IDie international Monetary System History of the International Monetary System 50 Contemporary Currency Regimes 56 Emerging Markets and Regime Choices 62 The Birth of a European Currency: The Euro 64 Exchange Rate Regimes: What Lies Ahead? 69 Summary Points 70 MINI-CASE: The Revaluation of the Chinese Yuan 71 Questions â⬠¢ Problems â⬠¢ Internet Exercises 74 50 Chapter 4 International Business Transactions: The BaBance of Payments Typical Balance of Payments Transactions: China 79 Fundamentals of Balance of Payments Accounting 80 The Accounts of the Balance of Payments 81 The Capital and Financial Account 83 The Balance of Payments in Total 89 The Balance of Payments Interaction with Key Macroeconomic Variables 91 Trade Balances and Exchange Rates 94 Capital Mobility 97 Summary Points 99 MINI-CASE: Turkeys Kriz (A): Deteriorating Balance of Payments 100 Questions â⬠¢ Problems D Internet Exercises 102 78 Chapter 5 Current Multinational Financial Challenges: The Credit Crisis of 2007-2009 106 The Seeds of Crisis: Subprime Debt 106 The Transmission Mechanism: Securitization and Derivatives of Securitized Debt 109 The Fallout: The Crisis of 2007 and 2008 120 xiv Contents xv The Remedy: Prescriptions for an Infected Global Financial Organism 129 Summary Points 131 MINI-CASE: Letting Go of Lehman Brothers 132 Questions D Problems â⬠¢ Internet Exercises 134 PART II Foreign Exchange Theory and Markets Chapter The Foreign Exchange Market 138 137 Geographical Extent of the Foreign Exchange Market 138 Functions of the Foreign Exchange Market 139 Market Participants 140 Transactions in the Interbank Market 142 Foreign Exchange Rates and Quotations 148 Summary Points 156 MINI-CASE: The Venezuelan Bolivar Black Market 157 Questions D Problems a Internet Exercises 160 Chapter? InternationaB Parity Conditions 164 Prices and Exchange Rates 164 Interest Rates and Exchange Rates 172 Forward Rate as an Unbiased Predictor of the Future Spot Rate 181 Prices, Interest Rates, and Exchange Rates in Equilibrium 183 Summary Points 184 MINI-CASE: Currency Pass-Through at Porsche 185 Questions â⬠¢ Problems â⬠¢ Internet Exercises 186 Appendix: An Algebraic Primer to International Parity Conditions 193 Chapter 8 Foreign Currency ierivatoves Foreign Currency Futures 198 Currency Options 201 Foreign Currency Speculation 203 Option Pricing and Valuation 210 Currency Option Pricing Sensitivity 213 Prudence in Practice 221 197 Summary Points 222 MINI-CASE: Warren Buffetts Love-Hate Relationship with Derivatives 223 Questions â⬠¢ Problems â⬠¢ Internet Exercises 226 Appendix: Currency Option Pricing Theory 230 Chapter 9 Interest Rate and Currency Swaps 234 Defining Interest Rate Risk 234 Management of Interest Rate Risk 237 Trident Corporation: Swapping to Fixed Rates 245 Currency Swaps 246 Trident Corporation: Swapping Floating Dollars into Fixed Rate Swiss Francs 247 Counterparty Risk 249 Summary Points 250 MINI-CASE: McDonalds Corporations British Pound Exposure 251 Questions n Problems â⬠¢ Internet Exercises 252 Chapter 10 Foreign Exchange Rate Determination and Forecasting Exchange Rate Determination: The Theoretical Thread 257 The Asset Market Approach to Forecasting 260 2S6 XVI Contents Disequilibrium: Exchange Rates in Emerging Markets 262 Illustrative Case: The Asian Crisis ^262 Illustrative Case: The Argentine Crisis of 2002 265 Forecasting in Practice 270 Summary Points 274 MINI-CASE: JPMorgan Chases Forecasting Accuracy 274 Questions â⬠¢ Problems â⬠¢ Internet Exercises 276 PART III Foreign Exchange Exposure 281 Chapter 11 Transaction Exposure 282 Types of Foreign Exchange Exposure 282 Why Hedge? 284 Measurement of Transaction Exposure 287 Tridents Transaction Exposure 289 Management of an Account Payable 297 Risk Management in Practice 299 Summary Points 300 MINI-CASE: Xian-Janssen Pharmaceutical (China) and the Euro 301 Questions D Problems D Internet Exercises 303 Appendix: Complex Options 312 Chapter 12 Operating Exposure 320 Attributes of Operating Exposure 320 Illustrating Operating Exposure: Trident 322 Strategic Management of Operating Exposure 326 Proactive Management of Operating Exposure 329 Contractual Approaches: Hedging the Unhedgeable 336 Summary Points 337 MINI-CASE: Toyotas European Operating Exposure 338 Questions a Problems a Internet Exercises 340 Chapter 13 Translation Exposure Overview of Translation 344 Translation Methods 347 Translation Example: Trident Europe 350 Comparing Translation Exposure with Operating Exposure 355 Managing Translation Exposure 355 Summary Points 359 MINI-CASE: LaJolla Engineering Services 360 Questions H Problems â⬠¢ Internet Exercises 362 PART IV Financing the Global Firm 365 Chapter 14 The Global Cost and Availability of Capita! 36à ® Weighted Average Cost of Capital 368 The Demand for Foreign Securities: The Role of International Portfolio Investors 373 The Cost of Capital for MNEs Compared to Domestic Firms 379 Solving a Riddle: Is the Weighted Average Cost of Capital for MNEs Really Higher Than for Their Domestic Counterparts? 380 Summary Points 382 MINI-CASE: Novo Industri A/S (Novo) 383 Questions D Problems â⬠¢ Internet Exercises 387 Contents xvii Chapter 15 Sourcang Equity Globally 391 Designing a Strategy to Source Equity Globally 392 Foreign Equity Listing and Issuance 395 Effect of Cross-Listing and Equity Issuance on Share Price 397 Barriers to Cross-Listing and Selling Equity Abroad 399 Alternative Instruments to Source Equity in Global Markets 400 Summary Points 404 MINI-CASE: Petrobras of Brazil and the Cost of Capital 404 Questions â⬠¢ Problems a Internet Exercises 408 Optimal Financial Structure 410 Optimal Financial Structure and the MNE 411 Financial Structure of Foreign Subsidiaries 414 International Debt Markets 418 Summary Points 424 MINI-CASE: Tirstrup BioMechanics (Denmark): Raising Dollar Debt 424 Questions â⬠¢ Problems o Internet Exercises 426 PART V Foreign Investment Decisions Chapter 17 431 International Portfolio Theory and Diversificationi. 432 International Diversification and Risk 432 Internationalizing the Domestic Portfolio 435 National Markets and Asset Performance 441 Summary Points 446 MINI-CASE: Is Modern Portfolio Theory Outdated? 447 Questions a Problems â⬠¢ Internet Exercises 448 Chapter 18 Foreign Direct Investment Theory and Political Risk Sustaining and Transferring Competitive Advantage 452 The OLI Paradigm and Internalization 455 Deciding Where to Invest 457 How to Invest Abroad: Modes of Foreign Involvement 458 Foreign Direct Investment Originating in Developing Countries 462 Foreign Direct Investment and Political Risk 464 Assessing Political Risk 465 Firm-Specific Risks 466 Country-Specific Risks: Transfer Risk 469 Country-Specific Risks: Cultural and Institutional Risks 472 Global-Specific Risks 476 Summary Points 479 MINI-CASE: Mattels Chinese Sourcing Crisis of 2007 480 Questions a Problems a Internet Exercises 483 452 Chapter 19 Multinational Capital Budgeting 487 Complexities of Budgeting forà a Foreign Project 488 Project versus Parent Valuation 489 Illustrative Case: Cemex Enters Indonesia 490 Real Option Analysis 502 Project Financing 503 Summary Points 505 MINI-CASE: Tridents Chinese Market Entryââ¬âAn Application of Real Option Analysis 505 Questions n Problems â⬠¢ Internet Exercises 507 xviii Contents PART VI Managing Multinational Operations Chapter 20 Multinational Tax Management 513 514 Tax Principles 514 Transfer Pricing 522 Tax Management at Trident 524 Tax Haven Subsidiaries and International Offshore Financial Centers 525 Summary Points 527 MINI-CASE: Stanley Works and Corporate Inversion 527 Questions â⬠¢ Problems n Internet Exercises 531 Chapter 21 Working Capital Management 535 Trident Brazils Operating Cycle 535 Tridents Repositioning Decisions 537 Constraints on Repositioning Funds 539 Conduits for Moving Funds by Unbundling Them 539 International Dividend Remittances 540 Net Working Capital 542 International Cash Management 548 Financing Working Capital 552 Summary Points 556 MINI-CASE: Honeywell and Pakistan International Airways 557 Questions â⬠¢ Problems n Internet Exercises 559 Chapter 22 Global Petroleum Development: Fiscal Regimes and Funding Financing Petroleum Development 566 Fiscal Regimes 566 Development Agreements 566 Concessions 569 Royalty/Tax Systems 570 Production Sharing Agreements 572 Service Agreements 574 Added Contractual Features 576 Top-Line Risks 578 Petroleum Prices 579 A Hypothetical Sub-Saharan PSA 581 PSA Evolution 584 Funding Petroleum Development 587 Summary Points 590 MINI-CASE: Petroleum Development and the Curse of Oil 590 Questions â⬠¢ Problems o Internet Exercises 593 565 Answers to Selected Problems Glossary Index 598 610 595 Credits 627
Sunday, October 27, 2019
Relationship between development and freedom
Relationship between development and freedom Sen, A (2001). Development as Freedom. Oxford. Oxford University Press. Chapter 1. The author conceptualizes development as ââ¬Ëthe gap between an exclusive concentration on economic wealth and a broader focus on the lives we can lead (p.14) emphasizing that the theory of development goes well beyond wealth accumulation and gross national product growth. The chapter examines the relationship between development and freedom, the way in which freedom is a component of development and an extensive view of ââ¬Ëfreedom encompassing both opportunities that people have and processes that allow for ââ¬Ëfreedom of decisions. The main arguments of the author is that development should be assessed by ââ¬Ëfreedom of accessibility to factors such as social opportunities, health care, clean water, economic security, civil rights and political freedom. Lack of accessibility means ââ¬Ëunfreedom. Development therefore should mean that people can live the lives they want to live and precisely, how can a nation say in all entirety that it has ââ¬Ëfreedom when its citizens cannot afford the very basic necessities of life or fulfill the rights they are entitled to? Sen goes on further to compare different views of poverty in both developing and developed nation by analyzing ââ¬Ëfreedoms through values, poverty and inequality, income and mortality, markets and freedom, tradition and culture. The author sees the process of development beyond economic growth or physical and human capital and concludes by linking the understanding of a broad view of the development process to the substantive ââ¬Ëfreedoms of people. Sens write up contains intriguing views but he hasnt mentioned what justifies his classification into these ââ¬Ëfreedoms i.e. experience of developing countries, factual historical evidence or how far ââ¬Ëfreedom has progressed within each context he identified. His definition is quite different from Rapleys in which Rapley describes development as more concerned with flexibility and adaptability (Rapley 2007 pp 5) and so raises a question. Can development be measured only by individual happiness without economic growth and stability? Happiness, in my opinion is geared more towards Rapleys definition and should be adapted into the process of economic growth. Willis, K. (2005) Theories and Practices of Development. London. Routledge. p. 32-42. Willis chapter 2 of theories and practices of development analyses development theories and practices and how these theories were attached to the economic, social and political theories that developed in Europe from the 18th century. Williss interpretation raises some interesting facts about historical development of theories and she divides her study into various theories. The classical economists such as David Ricardo, an advocate of free trade and Adam Smith, in his famous book, Wealth of Nations ââ¬Ëresponded to the trade focus of economic policy at that time (p.32) when trade was a major factor of economic growth. Here, protectionist measures such as high tariffs were highly used by merchants. Willis goes on to say Adam Smith was not in favour of this form of regulation and that it was harmful to the countrys economic growth. Instead, greater focus on production and division of labour which will be regulated by the ââ¬Ëinvisible hand of the market (p.33). The Great depression of the 1930s and other economic happenings gave rise to Keynes argument of the free market not necessarily a positive force but government intervention in the promotion of economic growth while postwar reconstruction period was a time to reflect on the economic crises that occurred at that time and provide solutions to their re-occurrence. This led to the creation of the Bretton woods institutions to assist in the promotion of ââ¬Ëstable economic growth within a capitalist system (p. 36) Willis describes the linear stages theory and makes emphasis on Rostow, the American economist and political theorists stages of Economic growth to development. Here, development was seen as a state where a large number of the population could afford to spend largely on consumer products and development was viewed as modern, moving from agricultural societies to an industrial economy. While she tries to decipher early theoretical ideas, Willis has not made clear linkages between some of these theories and how they have come to evolve in economic debates and discussions over time. Chang, H., and Ilene G. (2004) ââ¬ËReclaiming Development from the Washington Consensus, Journal of Post Keynesian Economics, 27(2), 274-291. The fundamental of this article is to correct the notion that there is no alternative to the Washington Consensus. The authors argue that ââ¬Ëneoliberal policies have failed to achieve their goals in developing world (p. 274) and so discuss the major development myths for justifying neoliberal policies that have been harmful to developing world and perhaps as a complacency to the reader, possible alternatives to these policies. These myths, evaluated individually, describe how these policies have lacked credibility. Myth 1; In contrast to the neoliberal policy success, the reality is that the policy has not promoted its main aim of economic growth. Myth 2; Developed countries gained success through free market policies whereas records claim they relied upon interventionist policies for development. Myth 3; Only neoliberal policies can succeed in todays global environment whereas in fact there is evidence of ââ¬Ëcontinuing institutional and policy divergence across national boundaries (p. 277) Myth 4; Discipline imposed by international institutions to keep them honest whereby placing policy making authority in the hands of these organizations. Myth 5; The East Asian model cannot be replicated when in fact most developed countries utilized this model. Myth 6; Developing countries should imitate the Anglo American model of capitalism which fared poorly in the economic boom of the 1990s. The authors went ahead to put forward alternative policies for faster economic development which includes the financial system providing adequate finance quantities for investment projects at appropriate prices, enforcing strict laws on new foreign loans incurred by domestic borrowers, defocusing on budget balance and maximizing FDI potentials to promote economic and industrial development in developing countries While arguing for these policies, it will be sensible to note that economies are different and there can be no ââ¬Ëbest practice policy that everyone should use (Chang 2003). Policies for development should not be ââ¬Ëfixed but depend on stages of development of a developing nation and other factors such as resource capacity, economic, political and social conditions. Pender, J. (2001) ââ¬ËFrom Structural Adjustment to Comprehensive Development Framework: Conditionality Transformed? Third World Quarterly, 22 (3), 397-411. Pender reviews how the World Banks approach to development has changed over decades and brought about important shifts to its conditionality approach. In the light of new changes between the 90s and today, the World Bank formulated a Comprehensive Development Framework, based on a relationship of partnership to replace its erstwhile structural adjustment lending (p. 397). The author examines why the World Banks perspectives of development changed through different periods; In the 1980s to early 90s, GDP was used as a measure of development as the Bank was mostly concerned with rapid economic growth and sustenance for least developed countries (LDC) and the adoption of policies such as restriction of state spending, controlling inflation, commodity exports and privatization as factors to achieve development. The 1990s drew lack of confidence in these policies and there were strong doubts about its competence judging from the success of the Asian Economies that developed rapidly without the World Banks policy prescriptions. This informed the Bank to change its 1980 view about minimal state role in development and that ââ¬Ëgrowth by itself is not enough (p 401). Thus in 1990, a formulation of an approach based on both ââ¬Ëlabour intensive growth and ââ¬Ëwidespread provision of basic social services (p.401). In spite of these alterations, there were criticisms that the Bank reforms were not aiding Africas growth but rather, increasing stagnant economies through the implementation of the Banks policies. According to Pender, the Bank lost confidence in its policy framework in early 1995, with the Asian miracle and LDCs failure and was forced to critique its own policies and re-orientate. This modification was experimented between 1995-1997 with ââ¬Ëimprovements in the understanding of economic development and poverty reduction as the central focus. The author gives clear informed views of the process of policy change within the World Bank at different times but fails to analyze the impact of this new focus of poverty reduction and its success to the development of todays third world countries. Chang, H. (2003) Kicking away the ladder. Development Strategy in Historical Perspectives. London, Anthem Press. Chapter 1. Changs analysis centers around one question, ââ¬ËHow did the rich countries really become rich? He uncovers some myths about developed countries developmental experience and argues that developed countries did not develop through the same policies that they recommend to the developing world. This pressure from developed countries to the developing world to adopt a set of ââ¬Ëgood policies that they adopted when they themselves were developing is faced with criticisms because ââ¬Ëhistorical evidence suggests otherwise and goes on to say that they are trying to hide the ââ¬Ësecret of their success (p. 2). Some of these policies include liberalization of trade, privatization, restrictive macroeconomic policies and deregulation but facts show that most of the developing countries used export subsidies and industry protection, industrial policies that the WTO disapproves in the present world. The USA and UK were examples of ardent users of these same ââ¬Ëpolicies frowned at in contrast to the free trade policies and free market they preach. Chang quotes List, the German economist that ââ¬ËBritain was the first country to perfect the art of infant industry promotion which is the principle behind most countries journey to success (p. 3). He argues that developed countries, while alleging to recommend good policies to developing countries are actually trying to ââ¬Ëkick away the ladder of their own economic development. A conclusion is drawn on some methodological issues of David Ricardos neoliberal policies to Friedrich Lists infant industry argument that while developed countries preach Ricardo to developing nations, they actually pursued Lists policies in the past. Although Chang did not confront and compare works of economic historians e.g. L.E Birdzells How the West grew rich in relation to his How did the rich countries really become rich to identify similar or different conclusions, his examination of historical materials to reach important and interesting conclusions is a contribution that is immensely valuable to the current debates on development that will evidently challenge contemporary policies and enrich development theory. REFERENCES Chang, H. (2003) Kicking away the ladder. Development Strategy in Historical Perspectives. London, Anthem Press. Chapter 1. Chang, H., and Ilene G. (2004) ââ¬ËReclaiming Development from the Washington Consensus, Journal of Post Keynesian Economics, 27(2), 274-291. Pender, J. (2001) ââ¬ËFrom Structural Adjustment to Comprehensive Development Framework: Conditionality Transformed? Third World Quarterly, 22 (3), 397-411. Rapley, J. (2007) Understanding Development: Theory and Practice in the Third World (3rd edition). Colorado. Lynne Reinner. Sen, A (2001). Development as Freedom. Oxford. Oxford University Press. Chapter 1. Willis, K. (2005) Theories and Practices of Development. London. Routledge. p. 32-42.
Friday, October 25, 2019
Interracial Dating Essay -- essays research papers
Many interracial couples are faced with negative reactions from society, making it hard for them to have a regular relationship. They have to deal with disapproval from their own race, pessimistic reactions from family and friends, and not to mention the ignorance of society as a whole. Why is interracial dating so controversial? Is not racism a thing of the past, or is that what we would like to believe? People who date and socialize with people of different racial groups frequently experience negative reactions. Many of the disapproving messages come from people of their own racial group. They scoff and make fun of the idea that they are dating someone with a different tone of skin or ethnic background. According to a poll taken in 1992, many people believe that people should date within their race to keep the unity within the ethnic community. It is like they believe in sequestering each racial group. They believe that every race is uniquely special and should not be integrated. Mixing races would only cause problems. Probably one of the most hurtful things in life is having to deal with family and friends who are not supportive of the people you truly like and love. One might wonder what may cause family and friends to rebel against interracial dating. As explained in Verna Stolkesââ¬â¢ book entitled Marriage, Class and Color in the 19th Century Cuba, many families may oppose the bonding of their loved one with someone of another race because of political reasons, religio...
Thursday, October 24, 2019
Puc 1st Year Model Question Paper
SHREE SHIVASHANKARA SWAMY GOVT. P. U. COLLEGE-UTTANGI:DIST:BELLARY MID-TERM EXAMINATION QUESTION PAPER NOVEMBER 2012 STD:PUC FIRST YEAR: SUB:ENGLISH: TOTAL MARKS: 90; DATE:26-11-2012 Q. NO I:Answer the following questions in a word or a phrase or a sentence each: 1X12=12 1)What was Steve crazy about? 2)Where did the bats live in large number? 3)Why did the narrator feel that his future was secure? 4)The animal without hands or legs refered to in the storyââ¬ËThe Rightful Inheriters Of the earthââ¬â¢is_______ a)Bat b)Cobra c)butterfly (choose the correct answer) 5)What was the formula given by Einstein for success? )How did the mother understand that her little daughter was dead in the church blast? 7)Who gave the cap to Steve? 8)In the poem ââ¬ËThe Ballad Of Birminghamââ¬â¢,the girl wanted to go to _________(fill in the blank) 9)Who broke the silence in the poem ââ¬ËFor Elkanaââ¬â¢? 10)The logician referred to in the poem ââ¬ËFor Elkanaââ¬â¢ is__________. a)Th e mother b)The father c)The son (choose the correct answer) 11)Where did Steve see his lost cap? 12)How much did the cap fetch for the Diamonds at last? Q.NO ||: Answer any eight of the following choosing atleast two questions from the poetry in 80-100 words each: 13)What were the different attitudes of the mother and the daughter about the Freedom March? 4X8=32 14)Describe Einsteinââ¬â¢s sense of humour. 15)How did the narratorââ¬â¢s wife try to kill the rats? What was the result of it? 16)Describe how Steve got the cap in the ball park. 17)Give two instances to explain Einsteinââ¬â¢s absent mindedness? 18)How did the son become a binding force between the father and the mother in the poem ââ¬ËFor Elkanaââ¬â¢? 9)Why did Steve have to lose the cap again in the Hudsonsââ¬â¢ house? 20)Describe the different interlopers into the narratorââ¬â¢s garden in the lesson ââ¬ËThe Rightful Inheriters Of The Earthââ¬â¢. 21)Why did the little girl go to Einsteinââ¬â¢ s house? How does this incident bring out Einsteinââ¬â¢sgreatness? 22)What was the effect of Steveââ¬â¢s finding the cap? Q. NO|||:Answer the following in about 200 words: 6X1=6 23)How did the narratorââ¬â¢s wife try to kill the bats? Why was she not successful? OR Describe how Dave and Steve were re-united at the end of the story ââ¬ËA Cap For Steveââ¬â¢.OR ââ¬ËEinstein was not only a great scientist, but also a great human beingââ¬â¢. Explain. Q. NO IV:Read the following passage and answer the questions set on it in a word /a phrase /a sentence each: 1X10=10 Alexander the Great is still considered as one of the greatest conquerors of the world. When Alexander was only 14 years old, he tamed the wild horse Bucephalus. Later, he rode this horse in all his battles. Alexanderââ¬â¢s father, Philip, became the king of Macedonia in 359BC. But he was murdered. After him, Alexander became the King at the age of 20.Alexander had received the training of warfare from his father. The great philosopher Aristotle was his intellectual mentor. The young Alexander attacked the Persian Empire in about 334BC. He achieved great victories and then attacked Egypt and established a city called Alexandria at the mouth of the river Nile. When Alexander entered Asia Minor, he married a rich and beautiful princess, Roxana. He fought his last great battle with the brave Indian King, Porus. He won this battle with great difficulties. He liked the courage and pride of Porus.He returned the kingdom of Porus and became his close friend. Alexander died in June 323 BC in Babylon. 24)Name the wild horse that Alexander tamed? 25)Who was Alexanderââ¬â¢s father? 26)At what age did Alexander become the king? 27)Who was the intellectual mentor of Alexander? 28)Alexander established a city on the bank of the river ____ a)the Ganga b)the Nile c)Amazon (choose the correct answer) 29)Name the city established by Alexander. 30)Whom did Alexander marry? 31)Name the Indian king who fought bravely against Alexander? 32)When did Alexander die? 3)Where did Alexander die? Q. NO. V:A)Fill in the blanks with appropriate articles and prepositions given in the brackets: 1X6=6 34) Einstein never missed __ opportunity to learn __ others. Once __ little school girl who lived __ his neighbourhood approached him __ his assistence. __ girl went __ Einsteins house. (a, an, the, to, for, from, in) B)Fill in the blanks with the suitable forms of the verbs given in brackets: 1X6=6 35) Steve told his parents that he _ _ (be + play )baseball in the park. When he__ (run) the bases, the cap __(fall)off.It was still too big despite the tuck his mother_ _(have + take)in the band. So the next time he __ (come) to bat, he __ it in his pocket. C)Choose the correct form of the verb given in bracket. 36)Bats __ (is / are) not the souls of our ancestors. 37)Nobody __ (know / knows)the right answer. 38)Both of them __ (were / was) in the same place. 39)The boy __ (has / have) a demand. 40)The mother __ (race / races) through the streets of Birmingham. 41)You __ (will / shall) never know it. 42)Mahatma Gandhiji __ (was / is) the father of our nation. 43)Owl __ (am / is) not a vegetarian creature.D)44)Write a letter to the principal of your college requesting him to issue your transfer certificate. Show the following reasons for your request: Your father has been transfered; You have taken admission in another college. E)Correct the following sentences and rewrite them: 45)I am loving my mother. 46)She has took her pen 47)Sachin is a best player. 48)My brother and I am coming. 49)You are there, are you? 1X5=5 5 1X8=8 ââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬â The End ââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âââ¬âà ¢â¬â
Tuesday, October 22, 2019
Authoritative Parenting Model Essay
Establishing discipline through authoritative parenting is an effective style because it displays secure emotional development, allows a higher quality of supportive peer relationships and enhances problem-solving skills for the child. Research has shown that authoritative parenting is the most effective style of parenting. Authoritative parenting is the one style that promotes equal involvement between the parent and child. (Cherry, 2013a). The parent displays fair discipline, warmth and nurturing, effective communication with the child and sets certain expectations on behavior and maturity. This parenting style promotes a ââ¬Å"democraticâ⬠model in which parents areà responsive to the childââ¬â¢s needs, thoughts and concerns. These parents will listen to questions the child may have on expectations set. Simply put by these parents are direct but not over bearing. (Cherry, 2013b). They reason instead of just punishing the child. Parents of this model want their children to be self-assured, socially approachable and cooperative. This furthermore, clearly defines that the authoritative style allows open communication between parent and child, love, guidance, nurturing, explanation of discipline and balance for the child. The authoritative parenting style is about setting limits, reasoning with kids, and being responsive to their emotional needs. (Dewar, 2013). These types of parents offer children a great deal of emotional support. While setting high standards for a child, parents who practice the authoritative style are responsive to the needs of children, demand children to show respect as well as provide a nurturing environment. In setting limits, children will often comply with respect to their parents and act responsibly. When children misbehave, the authoritative parent provides discipline as well and pointing out and discussing the misbehavior. The parent further provides reasoning to the act. In addition, parents allow for verbal responses and communicationà from the child that promotes a sense of balance. As Dewar further states, there is evidence that this style helps kids become more empathic, helpful, conscientious, and kind to others. Dewar also suggests, authoritative parents are both highly responsive and very demanding. Overall, this is one of the best ways to define the authoritative parenting style. Evidencedà research provides several conclusions that children raised by authoritative parents are more likely to become independent, socially accepted by peers, academically productive, and well mannered. (Dewar, 2013). Children often become more supportive, reliable, and thoughtful to family and peers. Authoritative parents promote secure attachments and allow children to communicate their concerns and feelings. In doing so, children are less likely to internalize problems. Talking with a child will allow them to verbalize both good and bad, learning from these better choices and avoiding future mistakes. In the end, children will become better with problem solving skills and positive emotional well-being. Authoritative parenting offers secure emotional development of a child. These parents exhibit respectable emotional understanding and control, encourage children to manage their own emotions and learn to understand others as well. (Cherry, 2013b). The authoritative parenting style focuses on parents listening to what their children have to say, place reasonable limits that have set consequences for certain behaviors and encourage an independent child. Parents are warm and welcoming to discuss anything with the child but do not do this in a robust manner. This parent is consistent with discipline but expects the child take responsibility for their actions. The parents do not judge or place immediate blame, they listen to what the child has to say. In return, these children tend to be capable of making appropriate decisions, have a sense of pride and happiness with themself and achieve goals set for them effectively. In other words, the authoritative parent encourages a child to set expectations of their own to succeed,à work through problems, develop their own skill sets and accomplish a strong sense of confidence. Diane Baumrindââ¬â¢s research shows that these children display a happier disposition, have effective control of their emotions, exhibit s social interaction and are self-starters in learning new things. (Cherry, 2013a). Multiple studies have been done that prove authoritative parents score high on measures of warmth and responsiveness and high on measures of control and maturity demands (Spera, 2005). This is likely due to the parentââ¬â¢s warm and responsive manner in which the child is approached by the parent. The parents due demand a high level of maturity from the child, but do so with balance, affection, and bidirectional communication to nurture relationships. The parent gives explanation of why a child should act a certain way in social or serious situation. Parents also help the child to prioritize what is important to succeed socially and academically. This is referred to as the demandingness/responsive model. (Spera, 2005). Demandingness refers to the demands parents make on their children to become unified with family and united in society with others. Parents hold certain levels of demand for their children, but provide direction, and discipline when appropriate. Responsiveness refers to parental actions that purposefully encourage individuality, self-confidence and contention of the child. With parental responsiveness, parents are receptive and understanding of the childââ¬â¢s needs. Parenting in this manner and with warmth and understanding, this can make a childââ¬â¢s temperament more calm, happy, adaptable, regulate sleeping and eating habits, set a positive mood and encourage interest in new experiences. Research has found that the best-adjusted children have parents with an authoritative style (Gurian, 2011). These parents are able to balance with definitions, place high demands with emotional responsiveness and maintain respect for their childââ¬â¢s independence. Parents need to remember though; children also have their own style and temperament. They doà react differently in given situations and parents must recognize those differences, especially in families with many siblings. Differences in these types of children are the easy going, calm, happy child who possess healthy habits, is generally in a good mood at all time and is interested in many different activities. In contrast, difficult child may be fussy, negative, and emotionally weak and get upset easily. Authoritative parents must understand the given situation and find a good ââ¬Å"fitâ⬠to meet the childââ¬â¢s demands. Being consistent is key as well. Setting limits on the child, providing ongoing encouragement, recognizing accomplishments, discussing solutions to problems and consistent communication is a must. Constructive conversation and encouragement with balance develop a strong relationship. Parents need to gain and maintain respect from their children to be able to teach them how to develop strong social relationships. Parents are the influential to child as they set limits and rules with respect to each individual in the family. A warm parent is full encouragement, bi directional communication, and love. (Harkey, 2012). The authoritative style is obviously the one that parents should strive for when parenting. When this type of parenting is accomplished a child will be happy, content and successful. Children will strive for balance and selfconfidence to develop strong peer relationships. Authoritative parents practice demandingness and response. They balance control and empathy that results in a thriving relationship with the child. These parents also do not put more on a child then they feel the child can handle. Again, they listen to the childââ¬â¢s needs and help them to make better decisions. Authoritative parent practicesà increase the importance of peer relationships for adolescents. This parenting style encourages a variety of positive outcomes for adolescents with quality, supportive friendships. (Beck, 2011). Peer friendships are important to all children especially in the adolescent years. Support from friends helps to develop a higher self-esteemà during this time and makes teens feel important. The authoritative parenting style promotes this as parents discuss school events, peer relationships and emotions with the child. Studies show that strong peer relationships are related to better social skills and develop leadership qualities in teens. (Beck, 2011). Parents encourage teens to become involved in these types of relationships. Parents encourage externalized communication, involvement in teen activities, questions about their peer relationships and strong communications. At the same time, parents demand certain behaviors and will not tolerate inappropriate teen behaviors. Parents must remember not to wait to form these bonds with children in the adolescent years; these bonds must being in early childhood and continued throughout the early adulthood years. Parents must also recognize that teens may begin to reference peers for advice and problem solving skills. Parent involvement without being over bearing is essential to maintain a balanced relationship with the child. Authoritative parenting is effective for positive outcomes of the child in problem solving skills as well as success with peer relationships (Spera, 2005). Spera reviews findings that speak to research of children from authoritative parenting styles and that are associated with positive schoolà outcomes. In his review of such research he suggests that authoritative parents provide many idea dynamics that lead to high academic performance. Authoritative parents provide a high level of emotional security. This allows the child a sense of comfort and helps them to succeed in their school and peer relationships. Spera also defines that authoritative parents provide their children with explanations for their actions. Explanations provide children with a sense of interpretation and mindfulness of their parentsââ¬â¢ values, morals, and goals. These are the building blocks to success in academic and social performance. Authoritative parents participate with the child in bidirectional communication. This style furthermore promotes better skills in interpersonal relations, sets a higher level of confidence and more popular children. Theseà interpersonal skills are a direct reflection of how a child will succeed in school, both socially and academically. Authoritative parents take a different, more moderate approach that emphasizes setting high standards, being nurturing and responsive, and showing respect for children as independent, rational beings. The authoritative parent expects maturity and cooperation, and offers children a lot of emotional support. Quality parenting is ongoing and offers warm and secure bonds between the parent and child. Children raised in this environment are less likely to internalize their feelings as authoritative parents encourage the child to talk about their thoughts and feelings. Also when a child makes a mistake, the parents must approach the situation in a caring manner vs. a blaming tone. This canà provide openness and solutions to problem solving and in turn children will become more effective learners from this process. Studies prove that encouraging independence in children reflect better problem solving skills and healthy emotional beings. (Dewar, 2010). This can provide the appropriate means for a child to become more helpful to others, caring and giving. In doing so, children will be viewed by peers as being kind, approachable and sometimes popular. The best-adjusted child, particularly in terms of social competence, has parents who utilize the authoritative, moderate parenting style. (Gurian, 2011). Gurian examines and compares the parenting styles researched for many years by Diane Baumrind that speaks to three different styles. These styles are authoritative, authoritarian and permissive parenting. Authoritative parenting, provides a balanced approach, demands expectations of appropriate behaviors, allow children to think through decisions and develop a sense of autonomy. Authoritarian patenting on the other hand, emphasizes strict discipline and severe punishment. Also, there is little affection shown. Permissive parenting, displays passionate warmth but this parent is hesitant to enforce rules. Gurian further explains that children from authoritativeà families tend to be emotionally sound, well behaved and competent in academic performance. This makes them resourceful, and socially adept in all aspects of life. In reference to children from authoritarian families, they are fairly well behaved but lack social skills. Also these children tend toà suffer from anxiety, unhappiness, and lack of self-confidence. Children from permissive families may hold a high self esteem but tend to get involved in problem behaviors such as drug or alcohol abuse and are poor performers in academics. Findings show that among all the components of personality, there is a direct and significant relationship between openness personality trait and authoritative parenting style. (Mohammad, Nasirudin, Samadzadeh and Amini, 2012). It aims to explore the difference in parenting styles and personality dimensions. This leads children to broaden their scope of curiosity and wisdom, which helps them with problem solving skills. The authors of this abstract (Mohammad, Nasirudin, Samadzadeh and Amini, 2012) clearly research and study over 272 students from a national university. They used random sampling and a questionnaire to gather the information to be reviewed from these students as the authoritative parenting style is one compared to the others that improves secure being, focus, knowledge, and develops problem solving. Also, in this study it reflects that the authoritative parenting style is the one compared to the others that improves secure being within the child, focus, and knowledge and develops problem-solving skills. Results of this study also showed that parentââ¬â¢s educational manners and styles are effective on the development of childrenââ¬â¢s personality behaviors. Parents play an important role in meeting a childââ¬â¢s needs. It is imperative that a parent provides a healthy relationship with child using the authoritative style of open communication, warmth and love. Self-confidence for child throughout life is significant in decision-making. Children with authoritative education style have higher social-emotional growth and better academicà achievement. Parents display social support, mutual relationships, approachability, responsiveness and satisfaction towards children with an authoritative parenting style. This in turn results in the maturity of these mechanisms within children. Family is definitely the main support of a childââ¬â¢s personality traits and growth. Parenting styles are patterns for childrenââ¬â¢s enhancement that is formed by the consistent communication of parent/child and how they response to childrenââ¬â¢s behavior. Authoritative parents demand maturity and accountability from the child, but approach them in a kind way with explanation at all times. Various studies discussed by (Mohammad, Nasirudin, Samadzadeh and Amini, 2012) speak to the committed relationship and authoritative parenting style that has a direct reflection on academic achievement in children. It also has a positive impact on the well-being and mental health of the child. These parents guide direction and provide explanation and solutions for further success of these children and therefore have a direct reflection on problem solving of adolescent issues. The article by (Spera, 2005) evaluates the information on the relationship among parenting practices, parenting styles, and adolescent school achievement. Spera speaks to research completed by Diane Baumrind that authoritative parents have high maturity demands and set expectations for achievement of their children. However, they foster maturity requests through bidirectional communication and encouragement of independence. The review of the practical research indicates that parental involvement and monitoring are strong predictors of adolescent achievement. Furthermore, the review specifies that authoritative parenting styles are often associated with advanced areas of student achievement. Parents find social skills important and entwine them in daily discussions with children. These topics can include social, academic and peer topics for discussion. Volunteering at school, helping children with homework and attending school events such as extracurricular activities are the many ways parents can stayà involved with child. Parents must initiate this type of involvement with children, as it will result in positive outcomes for the child. Moreover, Spera speaks to studies with adolescents that have found that parental assistance with homework is positively related to the amount of time adolescents spend on their homework. Parents who value the education as their child will result in those child to succeed in their academic practices as well as social interaction with peer groups (Spera, 2005). This results in personal and professional growth of the child. It also teaches children to respect their studies and understand why education is to be valued. Setting goals together can prove effective. Also, mature and self-confident children succeed with an authoritative parent if bidirectional communication is maintained. The abstract by (Turner, Chandler, and Heffer, 2009) also provides information about the effectiveness of appropriate parenting styles in relation to academic performance. The results of the current study of college students concludes that parenting characteristics such as concern, love and warmth continue to play an important role in prompting a studentââ¬â¢s academic performance while in college. It also speaks to self- esteem as it relates to success in college students. In doing so, it discusses research and studies that tested the interaction between child self-efficacy and authoritative parenting. In general, an authoritative parenting style emphasizing both responsiveness and demandingness appears superior in fostering higher academic performance. This provides reasoning as to why authoritative parenting is effective in the childââ¬â¢s progress through adolescence and early adulthood. Several other studies by Diane Baumrind have indicated that there is a positive link between authoritative parenting style and academic performance. These children are motivated constantly by their parents and provide ongoingà reassurance of goals and values. Authoritative parents encourage a high self-esteem and promote the ability for the child to mature, organize and achieve goals in a warm, secure way. These positive actions build success and growth for the child as they learn to work through problems, difficult scenarios and achieve success academically. Self-efficacy is strongly related to academic achievement especially at the college level. Again parents play an important role to assist in the development of maturity and self-assurance of the child beginning early in life. As children mature and begin on their own at the college levels, parents still can play an important role on the continued success. According to studies reviewed in the article of (Turner, Chandler, and Heffer, 2009). Students who come from an authoritative parenting style not only achieve overall academic success but tend to have a higher GPA. Ongoing research over the years shows that establishing discipline through authoritative parenting is one of the most effective styles because it provides secure emotional development, allows a higher quality of supportive social relationships and enhances problem-solving skills for the child. The authoritative parenting style is one in which parents display warmth, rationalization and understanding that provide a sense of security and self-perseverance of the child. These parents allow child involvement with an emphasis on bidirectional communication. Parents provide ideal problemà solving skills at all ages for future success by demanding maturity from the child but provide a positive and encouraging approach with balance to a develop strong peer relationships. Authoritative parents provide warmth, understanding and love to promote a childââ¬â¢s self confidence for overall academic and personal achievement throughout life. REFERENCES Beck, K. (2011). The role of mothersââ¬â¢ authoritativeà parenting in adolescent attachment and social relationships. [Abstract]. Cherry, K. (2013a). Parenting styles: the four styles of parenting. About.com Psychology. Retrievedfrom http://psychology.about.com/od/developmentalpsychology/a/paren ting-style.htm?r=et. Cherry, K. (2013b). What is authoritative parenting? About.com Guide to Psychology. Retrieved from http://psychology.about.com/od/childcare/f/authoritativeparenting.htm Dewar, G. (2013, March). The authoritative parenting style: Warmth, rationality, and high standards. A guide for the science-minded parent http://www.parentingscience.com/authoritative-parenting-style.html Dewar, G. (2010). Parenting styles: A guide for the science-minded http://www.parentingscience.com/parenting-styles.html Gurian, A. (2011, July). Parenting styles/childrenââ¬â¢s temperaments: the match. NYU Child Study Center. Retrieved from http://www.aboutourkids.org/articles/parenting_styleschildren039s_temperaments _match Harkey, N, & Jourgensen, T. (2012). Parenting by temperament: Authoritative parenting [Kindle edition]. Retrieved from Amazon.com Mohammad, M. Javidi, N., Samadzadeh, M. & Amini. M. ( 2012, September). 3332 Indian Journal of Science and Technology Vol. 5 No. 9 Spera, C. (2005). A review of the relationship among parenting practices, parenting styles, and adolescent school achievement. Educational Psychology Review, 17(2), 125-146 Turner, E., Chandler, M., Heffer, R. (2009, May/June). The influence of parenting styles, achievement motivation, and self-efficacy on academic performance in college students. Journal of College Student Development, Volume 50, (3), 337-346. Published by The Johns Hopkins University Press.
Martin Luther and John Calvin essays
Martin Luther and John Calvin essays Martin Luther and John Calvin were both very important men to the Reformation in Europe during the Renaissance and beyond. Although both Martin Luther and John Calvin were against the ideas of the Catholic Church, they had different views on social order and political authority in most cases. Martin Luther originated the ideas of the Reformation with his theory of justification by faith alone, which stated that one only needed faith in God in order to get into Heaven. Luther criticized the Catholic Church for creating their own practices or even superstitions, instead of following solely the teachings and practices of the Bible. He claimed that only two of the seven sacraments were valid, the Eucharist and baptism. Luthers views on social order went with the trend of other humanists of the time period. He believed in a more important role of the individual, an idea that differed radically with those of John Calvin. John Calvin was an extreme conservative, following the teachings of Martin Luther while also founding his own philosophies on social order. Calvin believed in predestination, the idea that it is predetermined who will be sent to heaven and who will be sent to hell. Calvin lived in Geneva for a period of time, setting its laws and guidelines for moral behavior. He was very intent on keeping Geneva as pure as possible. No drinking of alcohol, games, dancing or other immoral behavior would be permitted. Women also gained respect not found in other places in Europe. Men who beat their wives were severely punished. In most towns and cities what a man did with his wife was his own business; she was seen as a piece of property. These were the rules all Calvinists were to follow, with strict obedience. Martin Luther and John Calvin held more similar views on political authority than that of social order. Luther recognized secular power as valid and called for Christians to follow and obey the ...
Sunday, October 20, 2019
Test-Optional Colleges that Dont Require SATs
Test-Optional Colleges that Dont Require SATs If you got low SAT scores or low ACT scores, or if you simply didnt take the exam in time for application deadlines, realize that hundreds of test-optional colleges do not require entrance exams as part of their admissions applications. The list below is just a sampling of the roughly 850 four-year colleges that do not require the SAT or ACT. I have, however, included most of the highly selective schools that dont require scores. To see a complete list, visit the FairTest website. Also be sure to check out my list of 20 Great Colleges for Students with Low SAT Scores. Colleges dont use test scores for many reasons. Some technical schools, music schools and art schools dont see the ACT and SAT as good measures of the types of skills they require. Other schools recognize that the SAT and ACT limit their applicant pools and give an unfair advantage to students from schools or families that can afford test prep courses. You will also find on the FairTest list that many schools with strong religious affiliations do not require standardized tests. Admissions policies change frequently, so check with each school for the latest testing guidelines. Also, realize that some of the schools below are test-optional only for students who meet certain GPA or class rank requirements. Schools that dont require the ACT or SAT for some or all applicants American UniversityArizona State University at TempeArkansas State UniversityAustin Peay State UniversityBard CollegeBates CollegeBennington CollegeBowdoin CollegeCalifornia State University at Bakersfield, Chico, Dominguez Hills, East Bay, Fresno, Fullerton, Long Beach, Los Angeles, Monterey Bay, Northridge, Sacramento, San Bernardino, San Marcos, and StanislausBrandeis UniversityBryn Mawr CollegeClark UniversityCollege of the AtlanticCollege of the Holy CrossConnecticut CollegeDenison UniversityDePaul UniversityDickinson CollegeDrew UniversityEast Tennessee State UniversityEastern Kentucky UniversityFairfield UniversityFranklin and Marshall CollegeFurman UniversityGeorge Mason UniversityGettysburg CollegeGoddard CollegeGoucher CollegeGuilford CollegeGustavus Adolphus CollegeHampshire CollegeHobart and William Smith CollegesHofstra UniversityIllinois CollegeIndiana State UniversityIthaca CollegeJuniata CollegeKansas State University (scores required for out-of-state applicants)Kings College Knox CollegeLake Forest CollegeLawrence UniversityLewis Clark CollegeLoyola College in MarylandMarist CollegeMiddle Tennessee State UniversityMiddlebury College (SAT2 required if SAT1 is not used)Minnesota State UniversityMount Holyoke CollegeMuhlenberg CollegeNazareth CollegeNew School (scores required for some programs)Northern Arizona UniversityOhio State University at ATI Wooster, Mansfield, Marion, Newark (scores required for out-of-state applicants)Oklahoma State University, StillwaterOld Dominion UniversityPitzer CollegePresbyterian CollegeProvidence CollegeRobert Morris UniversityRoger Williams UniversityRollins CollegeSt. Johns College (Annapolis and Sante Fe)Sarah Lawrence CollegeSewanee: The University of the SouthSmith CollegeSouth Dakota State UniversityState University of New York at PotsdamStetson UniversityStonehill CollegeSusquehanna UniversityTemple UniversityUnion CollegeUniversity of Alaska at Anchorage, Fairbanks and SoutheastUniversity of ArizonaUniversity of A rkansas at Fortsmith, Little Rock, Monticello and Pine Bluff University of Idaho at MoscowUniversity of Kansas at LawrenceUniversity of Maine at Augusta, Farmington, Ft. Kent and Presque IsleUniversity of Minnesota at Crookston, Duluth and MorrisUniversity of MississippiUniversity of Montana at Missoula and WesternUniversity of Nebraska at Kearney and LincolnUniversity of Nevada at Las Vegas and RenoUniversity of Texas at Arlington, Brownsville, Dallas, El Paso, Pan American, San Antonio and TylerUrsinus CollegeWake Forest UniversityWashington CollegeWashington and Jefferson CollegeWesleyan UniversityWestern Kentucky UniversityWheaton College (MA)Wittenberg UniversityWhitworth UniversityWorcester Polytechnic Institute (WPI) When applying to schools, be sure to read their policies carefully. Some state schools on the list do require scores from out-of-state applicants. Other schools dont require scores for admissions, but they do use the scores for awarding academic scholarships.
Saturday, October 19, 2019
Meghalaya's Living Bridges Research Paper Example | Topics and Well Written Essays - 250 words
Meghalaya's Living Bridges - Research Paper Example Normal bridges are not viable in this region, as they would be damaged easily by rain of such magnitude. The living bridge gain strength with time and survive for a number of years. These bridges are strong and sturdy and can support even more than 50 people at once (BBC Series Web). Living bridges are only found in Meghalaya region and can hardly been seen in any other part of the world. This is considered unique and attracts a many people from various parts of the world. Actually, the Meghalaya community has been advised to continue nurturing the living bridges since they are a strong tourist attraction. The purpose of the living bridge is for people to go across rivers and streams during the rainy season that is estimated to be 25 meters. In addition, this region has many rivers that are fast flowing .Small rivers and streams rise above their normal height and become impassable on rainy season. These living bridges act as a solution to crossing such streams and bridges (BBC Series Web). These living bridges are complex in nature but managed and maintained by skillful biological engineering of roots of rubber
Friday, October 18, 2019
Disc Week Six Essay Example | Topics and Well Written Essays - 250 words
Disc Week Six - Essay Example A typical inductive reasoning relation to what Hacker describes would be the probability that it will be sunny at 12 noon. If for the case that the past three days it has been sunny at noon, then through generalization or inductive reasoning, then the fourth day would also be sunny. That is based on facts or a certain pattern that has occurred sequentially over a period of time. So upon collected facts that for three days it has been sunny, we can be assured to make a concrete assumption that the same will occur on the fourth day. Thus this is defined as inductive reasoning. Another assumption would be generalizing that an employee from company MMM who resides far from the work place will always come to work 30 minutes late. The assumption is that, if the employee has reported to work late on several instances that means through the generalization theorem, itââ¬â¢s probable that they are likely to do a repeat of same. The main motion behind inductive reasoning is that the assumption is based on a set of facts that have been previously encountered and the end product is a general
Final Exam Essay Example | Topics and Well Written Essays - 500 words - 7
Final Exam - Essay Example Affluent individuals can now also engage in a new relationship with strangers across the world that involves a larger community and stronger connections. Via new technologies at the work place, increased mobility, and international trade, people are now more interconnected than before. In addition to this economic interconnection, there is also environmental interconnection. We partake of the same natural resources; water and air, with people from less affluent countries. Because of this environmental and economic interconnection, the actions that we take are directly impactful on people in less affluent countries (Winfried & Pogge 34). Consumption on our side, as a global consumer of resources, affects the environment of those far and near. The actions we take have a consequence for others living in countries far from ours and we are responsible, causally, for the consequences, without regard of the place that they take place. Because our actions can bring environmental and economic harm to those living in less affluent countries and we remain unmoved by the suffering and pain inflicted on them, therefore; this is a brutish behavior (Winfried & Pogge 34). To act in a virtuous manner, however, would be showing compassion for them in a manner in which our close neighbors are not harmed. As people from affluent countries possess the capacity to be of aid, are members of a globalized community where actions affect those in less affluent countries and th e fact that failure to act would be an act of moral viciousness, we must act in order to alleviate severe poverty. While terrorism is an old practice, the war on the same is a new concept. The war on terror challenges prior conceptions on conflict, especially the theory of a just-war (Smit 23). While the question regarding whether the war on terror is just still remains unanswerable,
Culture Exercise Research Paper Example | Topics and Well Written Essays - 1250 words
Culture Exercise - Research Paper Example My great grandmother and her mother (both deceased) belonged to the Cherokee cultural group. My family is a nuclear one, and my mother (deceased) was the only child of my grandmother. My mother has three children including my sister and brother. My maternal grandmother is still living, and she is the head of the family where my elder sister, her two adult children, and five grandchildren live. My husband and I live in a separate house, and we have â⬠¦ children. Language formulations All our family members speak, read, and write English; it is the primary language we use. The closest language formulation I could identify is the use of slang by my family members. It seems that none of my family members uses the language of Ebonics. Some common Cherokee slang is unique to this Native American tribal group, and they have originated as local dialects within the US Cherokee communities. The slang we use may be unfamiliar to someone who does not belong to this family culture. Religious belief system My family of origin follows a particular religious belief system. Our religious practices or denominations include Baptist, Holiness, and Christian Methodist Episcopal. There are no additional special rituals. Religious belief is particularly important to the family because it notably influences the way the family members lead their life. Except the religious belief system, no specific philosophy is followed by my family. Admittedly, the intensity of religious belief is declining from generation to generation. Power holder in the family In our family culture, female is the head of the most of the households because male members are absent from family due to their choice. In some cases, male members are not present in the family due to increased substance abuse or imprisonment. Today, many African American leaders are vehemently working to make male members aware of the importance of family living. They also strive to enable women to choose mates who would help raise th e family. Although my grandmother is the matron of the family, each household enjoys the power to make its own decisions. Female members are the decision makers in the family because male members pay less attention to family affairs. Individual importance As per the current family structure, primary importance is given to individuals rather than the family unit. However, this family philosophy is subjected to changes under certain circumstances. To illustrate this, there is a shift of focus from individuals to the family unit with the death of my grandmotherââ¬â¢s brother on 22nd May 2013. Once everything associated with this death is resolved, the focus will be shifted to individuals again. Every individual has unique views; hence, he/she perceives and deals with things differently. I give more importance to the family unit than individuals. Therefore, I primarily focus on the needs of my grandmother, husband, and my children. Celebration of holidays The thanksgiving celebration is the major celebration of the family. For this celebration, every family member gathers at grandmotherââ¬â¢s home. Usually, we all do not gather at a place for any other celebration. However, it seems that family members living outside grandmotherââ¬â¢s home usually celebrate Christmas, Easter, and other special occasions at their own homes. Special rituals My grandmotherââ¬â¢s grandmother was a slave and was not allowed to practice her traditional ways. As a result, her children were
Thursday, October 17, 2019
Marketing Plan (Project about product) Essay Example | Topics and Well Written Essays - 500 words
Marketing Plan (Project about product) - Essay Example This would be done by live demos as well as online advertisement. Besides, this, we are including a depreciation cost of $5000 which includes depreciation of equipment as well as that of patents and copyrights. We also need to provide after-sales support to our clients to help them use the software and troubleshoot any bugs that arise. To start the business, we are aiming to acquire funding of $500,000. As shown in the balance sheet, apart from the usual assets in the business, the major assets of the business shall be patents and copyrights on our software and the software in the inventory. It is assumed that we shall keep a ready stock of 20 ready-to-deploy software copies in our stock. Also, we are assuming that 20% of the sales will be on credit as well as 20% of the expenses will be payable by us. At the first stage, we need to define the marketing goals for our business. For our software product, we have defined specific goals that we plan to achieve from our marketing program. Since we are just starting the business, as an overall marketing goal, we want to become the pioneers of producing and selling social CRM software for manufacturers of outdoor gears. Specifically, we would like to achieve the sales figure mentioned in the financial projection in terms of both sales amount and sales units. Further, since we are launching a unique product, we do not have any existing competition. However, we can set a target for ourselves to convince at least 10% of the existing outdoor gear manufacturers in using our software. If we achieve this target, we shall be able to meet our sales projection goals. As a further step for product awareness and publicity, we would want that at least 60% of our target market is aware of our product. Once we have established these goals, we need to define measures to evaluate our performance and identify the gaps. As a further step, we need to find out the causes of these gaps. To evaluate our
Slavery in British North America and the Caribbean Essay
Slavery in British North America and the Caribbean - Essay Example While slavery certainly had some significant economic factors, and which were vastly different in the north from the south, the fact remains that slavery was primarily an institution based on race and dehumanization rather than economics. Slavery in the northern and southern colonies were very different institutions, largely because of the divergent economic development that occurred in those areas. In the northern colonies, cash crops were not the staples of the economy, rather manufacturing and other early industrial practices reigned supreme. These are areas that were not especially suited to the practice of slavery, because they needed highly skilled, willing workers. In this economy slaves usually served either in service professions (maids and so forth) or else as assistants, but were not fundamental to the economy and could easily be changed into low-paid workers. In the south, on the other hand, much of the economy developed around a select group of cash crops, most importantly tobacco and cotton. These crops were both some of the most labor-intensive crops to develop ââ¬â cotton especially took hundreds of hours to pick and process before the development of the cotton gin in the later 19th century. This m eant that the southern economy found slavery an especially useful convention, and began building itself more and more around having plentiful unpaid labor. The huge amount of slaves that were involved in the development of the southern colonies also meant that any attempt to move away from the practice of slavery would be especially costly ââ¬â instead of a business having to pay one or two extra employees, they would have had to pay hundreds, and vastly improve working conditions. This meant that slavery became a much more prolific and important structure in the south than in the north.
Wednesday, October 16, 2019
Culture Exercise Research Paper Example | Topics and Well Written Essays - 1250 words
Culture Exercise - Research Paper Example My great grandmother and her mother (both deceased) belonged to the Cherokee cultural group. My family is a nuclear one, and my mother (deceased) was the only child of my grandmother. My mother has three children including my sister and brother. My maternal grandmother is still living, and she is the head of the family where my elder sister, her two adult children, and five grandchildren live. My husband and I live in a separate house, and we have â⬠¦ children. Language formulations All our family members speak, read, and write English; it is the primary language we use. The closest language formulation I could identify is the use of slang by my family members. It seems that none of my family members uses the language of Ebonics. Some common Cherokee slang is unique to this Native American tribal group, and they have originated as local dialects within the US Cherokee communities. The slang we use may be unfamiliar to someone who does not belong to this family culture. Religious belief system My family of origin follows a particular religious belief system. Our religious practices or denominations include Baptist, Holiness, and Christian Methodist Episcopal. There are no additional special rituals. Religious belief is particularly important to the family because it notably influences the way the family members lead their life. Except the religious belief system, no specific philosophy is followed by my family. Admittedly, the intensity of religious belief is declining from generation to generation. Power holder in the family In our family culture, female is the head of the most of the households because male members are absent from family due to their choice. In some cases, male members are not present in the family due to increased substance abuse or imprisonment. Today, many African American leaders are vehemently working to make male members aware of the importance of family living. They also strive to enable women to choose mates who would help raise th e family. Although my grandmother is the matron of the family, each household enjoys the power to make its own decisions. Female members are the decision makers in the family because male members pay less attention to family affairs. Individual importance As per the current family structure, primary importance is given to individuals rather than the family unit. However, this family philosophy is subjected to changes under certain circumstances. To illustrate this, there is a shift of focus from individuals to the family unit with the death of my grandmotherââ¬â¢s brother on 22nd May 2013. Once everything associated with this death is resolved, the focus will be shifted to individuals again. Every individual has unique views; hence, he/she perceives and deals with things differently. I give more importance to the family unit than individuals. Therefore, I primarily focus on the needs of my grandmother, husband, and my children. Celebration of holidays The thanksgiving celebration is the major celebration of the family. For this celebration, every family member gathers at grandmotherââ¬â¢s home. Usually, we all do not gather at a place for any other celebration. However, it seems that family members living outside grandmotherââ¬â¢s home usually celebrate Christmas, Easter, and other special occasions at their own homes. Special rituals My grandmotherââ¬â¢s grandmother was a slave and was not allowed to practice her traditional ways. As a result, her children were
Tuesday, October 15, 2019
Slavery in British North America and the Caribbean Essay
Slavery in British North America and the Caribbean - Essay Example While slavery certainly had some significant economic factors, and which were vastly different in the north from the south, the fact remains that slavery was primarily an institution based on race and dehumanization rather than economics. Slavery in the northern and southern colonies were very different institutions, largely because of the divergent economic development that occurred in those areas. In the northern colonies, cash crops were not the staples of the economy, rather manufacturing and other early industrial practices reigned supreme. These are areas that were not especially suited to the practice of slavery, because they needed highly skilled, willing workers. In this economy slaves usually served either in service professions (maids and so forth) or else as assistants, but were not fundamental to the economy and could easily be changed into low-paid workers. In the south, on the other hand, much of the economy developed around a select group of cash crops, most importantly tobacco and cotton. These crops were both some of the most labor-intensive crops to develop ââ¬â cotton especially took hundreds of hours to pick and process before the development of the cotton gin in the later 19th century. This m eant that the southern economy found slavery an especially useful convention, and began building itself more and more around having plentiful unpaid labor. The huge amount of slaves that were involved in the development of the southern colonies also meant that any attempt to move away from the practice of slavery would be especially costly ââ¬â instead of a business having to pay one or two extra employees, they would have had to pay hundreds, and vastly improve working conditions. This meant that slavery became a much more prolific and important structure in the south than in the north.
My Definition of Success Essay Example for Free
My Definition of Success Essay Success is not an eventual pinnacle. It is an odyssey that has multiple peaks, and at each peak one must strive to attain his goal and culminate his efforts into something fruitful. Different people have myriad opinions about success. Some relate it with money, some with power. However, for me ââ¬Å"success is peace of mind, which is a direct result of self-satisfaction in knowing you made the effort to do your best, to become the best of that you are capable of becoming. â⬠It consists in being content with what you do!! Success is something one assembles from components he discovers in his soul and his imagination. It can be achieved by knowing, understanding, believing in oneself, and executing the apposite actions required to achieve it. ââ¬Å"The truth is that all of us attain the greatest success and blithe possible in this life whenever we use our native capacities to their greatest extent. â⬠ââ¬Å"Do not aim for success if you want it! Just do what you love and believe in, andâ⬠¦it will come naturally. â⬠Sorrowfully, success has been commercialized with fame and popularity. ââ¬Å"The common idea that success spoils people by making them vain, egotistic, and self-complacent is erroneous; on the contrary it makes them-for the most part- humble, tolerant, and kind. Setbacks also help in achieving success. It is very aptly said that discouragement and failure are two of the surest stepping stones to success. Multi-faceted success doesnââ¬â¢t lie in not falling, but lies in rising each time you fall. If we become dejected, we will be in nadir and will lose the hope to ever rise again. It is imperative that we take our failures in our stride, which will actuate us to accomplish our tasks. Having done so, we can set an inspiring example and leave an indelible imprint on the minds of others to emulate.
Monday, October 14, 2019
Efficacy of Growth Factors Concentration after PRP
Efficacy of Growth Factors Concentration after PRP Efficacy of growth factors concentration (hGH, IGF-1, FGF-2, PDGF, VEGF) after autologous Platelet-rich plasma injection (PRP) on accelerating healing of proximal hamstring tear for athletes. Ahmed Gaballah 1- Department of Sports Health Sciences, Damietta University, Damietta, Egypt. 2- Kinesiology and Health Sciences Department, Utah State University, Logan, UT, USA Abstract Platelet rich plasma (PRP) become popular biologically method used to accelerate healing in sports medicine and orthopaedic surgery field. PRP is concentrate the human platelets to supra-physiologic levels. It is an autologous producing high level of the platelets concentration centrifuged from the peripheral vein. Then it re-injected under the ultrasound gaudiness during surgery or at a site of injury. METHOD: Seventeen physically active males (age 22.0à ±0.6) with acute hamstring strain injuries divided to 8 case group and 9 matched controls (age 21.6à ±2.8) were recruited as research participants. Case group participants were injected with single 3 ml of extracted PRP under ultrasound gaudiness. However, Blood samples were collected by venipuncture at standardized time points: before the injection and 24, 48, 72, and 96 hours after for case group and 4wks. and 8wks for both groups. RESULTS: there was significantly difference between the growth factors results of the case group a fter 4 weeks compared with the 8 weeks result of the control group. Additionally, the same significant results between the two groups after the 8 weeks. Nevertheless, the physical measurements related with hamstring Strain and Knee flexion range of motion between the two groups were not significant after 4 weeks or 8 weeks. CONCLUTION: a single 3-mL injection of autologous PRP combined with a rehabilitation program was effective in time return to play and reducing the severity of pain after an acute grade 2 hamstring injury. Additionally, increase in circulating concentrations of VEGF, IGF-1, PDGF and FGF-2. Key Words: Platelet rich plasma (PRP), Human Growth Factors, Hamstring Tear. 1. Introduction: Skeletal muscle injuries are up to 55% of all sports injuries and causes excessive long term pain and physical disability, Muscles strains and contusions representing more than 90% of all sports related injuries and are the most muscular injuries frequent. [1] [2]à Proximal hamstring tear injuries are common in athletes and frequently result in prolonged rehabilitation, time missed from play, and a significant risk of re-injury. Reports of acute hamstring strains without avulsion in dancers have suggested recovery times for return-to-play ranging from 30 to 76 weeks [3]. Platelet rich plasma (PRP) become popular biologically method used to accelerate healing in sports medicine and orthopaedic surgery field. PRP is concentrate the human platelets to supra-physiologic levels. It is an autologous producing high level of the platelets concentration centrifuged from the peripheral vein. Then it re-injected under the ultrasound gaudiness during surgery or at a site of injury [4] [5]. As a result of the lack side-effect and the autologous nature of PRP, it has utilized exponentially over the last few years in sports medicine and orthopaedic. Historically, since the 1950s the platelet-rich plasma (PRP) has been used to dermatological conditions and manage maxillofacial as well [6]. Furthermore, Platelet-derived preparations including PRP were first regulated by WADA under the 2010 Prohibited List because of concerns that the elevated concentrations of growth factors in PRP may confer an unfair advantage to treated athletes. However, WADA lifted the ban on PR P in 2011 in recognition of the lack of evidence to support a systemic performance-enhancing effect and to allow further research in the field [7]. Indeed, the blood contains 6% platelets, 1% white blood cells, and 93% red blood cells.à The PRP technique aims to reverse the concentration of the platelet in lieu of red cells to increase the growth factors that more useful in accelerating the healing. [8] However, Platelet rich plasma (PRP) is a centrifuged blood product that contains a supraphysiologic amount of platelets. Therefore, the preparation process to product concentrative platelet above the baseline values have started with an autologous extraction of patients` blood, then by plasmapheresis centrifuged to obtain a concentrated suspension of platelets. It then separates the solid and liquid components of the anticoagulated blood after a two-stage of centrifugation process [9]. The initial phase separates the plasma and platelets from the erythrocytes and leucocytes. The second stage concentrates the platelets further into platelet-rich and platelet-poor plasma components [10] [11]. Platelet rich plasma (PRP) contains some biologic factors which have been enhanced the proliferation and collagen secretion of tenocytes. These factors including vascular endothelial growth factor (VEGF), basic fibroblast growth factor (FGF2), and transforming growth factor à ² (TGF à ²) [12] [13]. There is an increasing the stimulus response of PDGF and TGF-à ² in the early stages of tendon and muscles healing after PRP injection resulting in new vessel formation and collagen synthesis. [14]. In addition to decrease oxidative stress that could lead to cell apoptosis, PRP has been promoted tendon and muscles cell growth [15]. This is evidenced and reinforced by release of inflammatory meiators such as COX-1 and2, PGE-2 [16] [17]. Recently, there are various approaches reported the benefits of treating the soft tissue injuries such as muscles tears and tendinosis by injecting platelet rich plasma (PRP). Despite this popularization and increasing use in soft tissue injuries, its efficacy still not clear and remains controversial. It has been previously established that platelets provide regenerative potential by the process of chemo-taxis [18] [19] [20]. The use of PRP in order to accelerate recovery time after muscle injury has become a relatively common practice in sports medicine. Several studies represent that PRP can improve skeletal muscle healing after acute injury. In particular, local PRP which increased expression of several myogenic factors at mRNA level acting on modlating the inflammatory response and myogenesis in the early stages after acute injury [21] [22]. Rossi L, et al. reported the effects of an autologous PRP injections on time to return to play in randomized controlled study conducted on 75 patients. The study represented time to return to play for recreational and competitive athletes and recurrence rate after acute muscle injuries as well. The main result in the study that PRP injection significant reduction of re-injury rates at 2 years. Additionally, it was decreased the pain severity score and significantly decreased the time of return to sports as well [23]. One more study reported that 14 professional athletes were treated with ultrasound-guidance injections of PRP after acute muscle injuries. The athletes showed a quick return to activity and improved healing in muscle tears [8]. Similar results have represented in Sanchez et al study, which conducted on 20 athletes. These results supported the benefits of PRP and its role in muscle healing. The patients recovered in half of the expected time [24]. Figure 1. Process of platelet activation (PDGF, platelet derived growth factor). Source [25] Platelet Activity in muscles: (Figure 1,) represents the released serotonin contributes to vasoconstriction. The conversion of ATP into ADP releases the energy necessary to establish and maintain the aggregation. The release of the calcium ions inside the platelet makes the myofibril within it contract, thus allowing the aggregation and release of the content of the granules. This is serum calcium, which is necessary for the formation of the fibrin network [26]. The presence of the Ca2+ ions in the plasma makes the coagulation factors activate and group, forming the fibrin network, which is stabilized by factor XIII and transformed in a stable clot. The calcium ions also inhibit the anticoagulant activity of heparin, preserving the clot [27]. The PRP and the growth factors: The functions of these growth factors are presented in Table 1. It should be noted that the mechanism of action of platelet-rich plasma does not differ from the physiological healing process, but allows for obtaining higher concentrations of growth factors. As a result, the process of tissue regeneration is accelerated [28] [29] [30]. Platelet à ±-granules are comprised of haemostatic factors, regulators inflammation, and wound healing. Substances stored in dense granules are thrombocyte-activating factors. Platelets also contain lysosomal granules, which secrete acid hydrolases [31] [32]. Platelet activation results in growth factor release. Platelet growth factors include platelet-derived growth factor (PDGF), transforming growth factor à ² (TGF-à ²), vascular endothelial growth factor (VEGF), epidermal growth factor (EGF) and insulin-like growth factor 1 (IGF-1) [33] [8]. Table 1. Growth Factors function Growth factor Abbreviation Functions Transforming growth factor TGF-à ² A mitogen for fibroblasts, smooth muscle cells, osteoblasts Angiogenesis promotion, extracellular matrix production Platelet-derived growth factor PDGF Chemotactic effect on monocytes, neutrophils, fibroblasts, mesenchymal stem cells and osteoblasts A mitogen for fibroblasts and smooth muscle cells Angiogenesis promotion, formation of fibrous tissue, re-epithelialization Vascular endothelial growth factor VEGF Angiogenesis promotion Chronic wound healing promotion Inhibition of bone formation Epidermal growth EGF factor A mitogen for fibroblasts, endothelial cells, keratinocytes Chronic wound healing promotion Insulin-like growth factor IGF-1 Regulation of bone maintenance Modulator of cell apoptosis Stimulation of bone tissue regeneration Platet derived endothelial growth factor PDEGF Promotes wound healing by stimulating the proliferation of keratinocyes and dermal fibroblasts Endothelial Growth Factor EGF Cellular proliferation Differentiation of epithelial cells Figure 2. Platelet degranulation and action of the released cytokines in the process of formation of new bone and muscle tissue (VEGF, vascular endothelial growth factor; PDGF, platelet derived growth factor; BMP, bone morphogenetic protein; TGF-b, transforming growth factor). 2. Methods 2.1. Participants: This study was approved by Damietta University, Egypt, Alexandria University, Egypt and Utah state University, UT, USA. Twenty-three physically active males with acute grade 2 hamstring tear were voluntarily recruited for data collection (age 21.8 à ± 2.64y, mass 71.52à ±2.74 Kg, height 175.4à ±2.32). All patients receiving local ultrasound-guided intratendinous PRP injection at our institution between September 2014 and December 2016 were screened for eligibility to participate in the study, and 17 patients were ultimately enrolled. Exclusion criteria included five participants with previous injury or diagnoses in hamstring. 8 physically active males (age 22.0à ±0.6) with acute hamstring strain injuries and 9 matched controls (age 21.6à ±2.8) were recruited as research participants. The case and control groups were performed rehabilitation program included aquatic exercise for 8 weeks. The history of pain data and the daily hours of using the smartphones were collected by surve y. Furthermore, the procedures were explained to the subjects and their written signatures were obtained on the informed consent. 2.2. Platelet rich plasma preparation and injection: In accordance of GPSTM III Systems instruction the blood collected for PRP was prepared by (Biomet Biologics, Inc., Warsaw, Ind) and standard 60 ml GPSTM III kit. Approximately of 7 ml of PRP was prepared in 30 minutes. Furthermore, single 3 ml of extracted PRP were injected under ultrasound gaudiness after adding 8.4% sodium bicarbonate buffered PRP for increasing the pH to normal physiological levels. The sodium was added in a ratio 0.05 ml to 1 ml of PRP. All the participants blood samples were stored in -25à ° Celsius and were analyzed to determine the concentration of the growth factors. The PRP injection of the current study were injected directly into the injured area under aseptic technique. The case group participants only received the single autologous PRP combined with the rehabilitation program. The participants were kept under observation for 96 hours and were performed the rehabilitation program after 5-7 days of PRP injection. Blood samples were collected by venipuncture at standardized time points: before (baseline) and 24, 48, 72, and 96 hours to 4wks. and 8wks. after administration of PRP. blood was drawn at precisely the same time each morning and at least 3 hours after eating and exercising per WADA standards Figure 3. PRP set up. 2.3. Growth Factor Quantification: Six growth factors and related molecules that are concentrated in PRP preparations were quantified in PRP and blood by direct immunoassay using the Quantikine enzymelinked immunosorbent assay (ELISA kit), as outlinedà the Growth factors studied were: human growth hormone (hGH), insulin-like growth factor-1 (IGF-1), insulin-like growth factor binding protein-3 (IGFBP-3), basic fibro blast growth factor (bFGF or FGF-2), vascular endothelial growth factor (VEGF), and platelet-derived growth factor- BB (PDGF-BB). Because bFGF is present in the blood only at very low concentrations, a high-sensitivity ELISA kit was used to ensure accurate detection [34] [35] [5]. Figure 4. PRP injection under ultrasound guidance. 2.4. Rehabilitation program: A Physical rehabilitation program was performed for six weeks and designed for lower limb. In particular, hamstring muscles. both groups participants (8 case and 9 control) performed the exercises protocol once a day for 55 minutes for each training session and 5 times a week (275 M. / week). The exercise protocol was consisted of aquatic exercise and strength exercises and was divided to tree stages, the first stage was focused on the flexibility and isotonic strength exercise with 5 sets and 12-15 1RM intensity. While, the second stage was designed for strength exercises with 3 sets and 8-10 1RM intensity. While the third stage for endurance and exercise related of activity performance. Aquatic pool, Machine weights and The Thera-Band resistance bands exercises were used during the 6 weeks especially the colors (red, blue, black, silver). The red and blue bands were used in the first stage and the black and silver used in second stage. Furthermore, all the exercises were performed by stretching the band between 75 100 %. knowing that, the weight of stretching in Thera-Band between 75-100% is red 3.3-3.9kg, blue 5.9-7.1kg, black 8.1-9.7, and silver 11.1-13.2kg. 2.5. Statistical Analysis The paired t-test was used to compare the collected data before performing the exercise protocol (Pre-test) and those which were obtained after the 6 and 8-weeks training period (Post-test). The differences between the samples were significant at the t = 1.740 p < 0.05 level. All the analyses were performed by using SPSS 21 software for Windows 7 (SPSS Inc. Chicago, IL, USA). Additionally, all values within the text and table are observed as standard deviation and mean (mean à ± SD). 3. Results: Table 2, 3 illustrate the large variations in growth factor concentrations between participants in the two groups before and after PRP injection. Regarding growth factor (GF) trajectories for the case group participants are shown in Figure 3, and data are summarized in Table 2, the human growth hormone increased dramatically within the first 24 hours after PRP injection while these results were not significant after the 4 weeks and 8 weeks.à Moreover, IGF-1 increased relative to baseline within 24 hours after PRP and remained elevated at all-time points thereafter, and the change was statistically at 24 until 96 hours as well after 4 weeks and 8 weeks. Likewise, VEGF and PDGF were significantly elevated at 24 hours and at all-time points thereafter and were significant after 4 and 8 weeks.à Furthermore, FGF-2 rose at the point between 24 to 96 hours after PRP injection but not significantly, while it was elevated significantly after 4 week and 8 weeks. It obviously represented in table 3, the spectacular significantly difference between the growth factors results of the case group after 4 weeks compared with the 8 weeks result of the control group. Additionally, Figure 6, reveals the same significant results between the two groups after the 8 weeks. Nevertheless, the physical measurements related with hamstring Strain and Knee flexion range of motion between the two groups were not significant after 4 weeks or 8 weeks. Table 1. Data Summary for the Growth Factors after PRP Injectiona unit à à à Pre-test 24 h 48 h 72 h 96 h 4 weeks 8 weeks hGHà pg/mLpg/mL pg/mL 1.927 à ± 0.67 8.117 à ± 2.414 2.276 à ± 0.030 2.776 à ± 0.180 5.597 à ± 1.910 2.321 à ± 0.554 2.175 à ± 0.651 IGF-1 pg/mL 0.577à ±0.283 1.078 à ± 0.914 1.101à ±0.341 1.122 à ± 0.239 1.133 à ± 0.165 0.817 à ± 0.844 0.793 à ± 0.141 FGF-2 pg/mL 2.233 à ± 1.22 2.105 à ± 0.772 2.292 à ± 0.736 1.911 à ± 0.201 2.314 à ± 0.877 3.652 à ± 0.567 3.921 à ± 0.822 VEGF pg/mL 0.346 à ± 0.18 1.313 à ± 0.42 1.544 à ± 0.463 1.836 à ± 0.463 1.554 à ± 0.419 0.784 à ± 0.098 0.749 à ± 0.077 PDGF pg/mL 0.352à ±0.11 0.884 à ± 0.949 1.702à ±1.572 1.602 à ± 2.021 1.262 à ± 1.423 0.856 à ± 0.108 0.807 à ± 0.133 aPRP, platelet-rich plasma; hGH, human growth hormone; IGF-1, insulin-like growth factor-1; FGF-2, basic fibroblast growth factor; VEGF, vascular endothelial growth factor; PDGF, platelet-derived growth factor. Table 2. Difference of the Growth Factors concentration between the Case and Control group Case Group (N=8) Control Group (N = 9) Unit Pre-test 4 weeks 8 weeks Pre-test 4 weeks 8 weeks P âⰠ¤ 0.05 hGHà pg/mLpg/mL pg/mL 1.927 à ± 0.67 2.321 à ± 0.554 2.175 à ± 0.651 1.941 à ± 0.201 1.997 à ± 0.088 2.063 à ± 0.477 1.215 IGF-1 pg/mL 0.577à ±0.283 0.817 à ± 0.844 0. 793 à ± 0.141 0.582 à ± 0.247 0.633 à ± 0.145 0.637 à ± 0.114 1.760 * FGF-2 pg/mL 2.233 à ± 1.22 3.452 à ± 0.567 3.921 à ± 0.822 2.228 à ± 0.721 2.593 à ± 0.687 2.627 à ± 0.514 2.046 * VEGF pg/mL 0.346 à ± 0.184 0.784 à ± 0.098 0.749 à ± 0.077 0.341 à ± 0.163 0.384 à ± 0.187 0.396 à ± 0.106 2.584 * PDGF pg/mL 0.352à ±0.117 0.856 à ± 0.108 0.807 à ± 0.133 0.358 à ± 0.121 0.421 à ± 0.633 0.429 à ± 0.008 2.632 * PRP, platelet-rich plasma; hGH, human growth hormone; IGF-1, insulin-like growth factor-1; FGF-2, basic fibroblast growth factor; VEGF, vascular endothelial growth factor; PDGF, platelet-derived growth factor; N, Number; * Significant difference P âⰠ¤ 0.05, t =1.740 (N= 17). Table 3. Difference of Hamstring Force and Knee Flexion (ROM) between the Case and Control group Case Group (N=8) Control Group (N = 9) Unit Pre-test 4 weeks 8 weeks Pre-test 4 weeks 8 weeks P âⰠ¤ 0.05 HF N 26.62 à ± 4.67 104.32 à ± 5.67 107.06à ±1.64 25.31 à ± 3.41 102.71 à ± 4.75 105.75 à ±3.18 0.743 KF(ROM) Deg. Ãâ¹Ã
¡ 51.72 à ± 5.17 147.92 à ± 0.43 148.62 à ± 0.78 52.04 à ± 2.43 147.02 à ± 0.14 147.36 à ± 0.88 0.632 aPRP, platelet-rich plasma; HF, Hamstring Force; KF(ROM), Knee Flexion range of motion. N, Number. P âⰠ¤ 0.05, t =1.740 (N= 17). 4. Discussion: There is little published evidence to support whether a statistically significant increase in growth factors with performance-enhancing potential, including IGF-1, hGH VEGF, PDGF and FGF-2, necessarily leads to clinically relevant ergogenic effects. This is further complicated by evidence from some animal studies that local IGF-1 overexpression enhances local muscle mass and strength without systemic increases in IGF-1. The current study aims to determine the effect of PRP in accelerate the healing of hamstring strain. Moreover, to identify potential molecular markers that could be used to distinguish athletes who have been treated with local PRP injections from those who have not. Figure 5, The concentration of the growth factors after the PRP injection. PRP, platelet-rich plasma; hGH, human growth hormone; IGF-1, insulin-like growth factor-1; FGF-2, basic fibroblast growth factor; VEGF, vascular endothelial growth factor; PDGF, platelet-derived growth factor. The performance of the growth factors after a single PRP injection was enhanced and increased significantly from 24 until 96 hours.à Indeed, hGH was peaked within the 24-hour window, although the results were not significant after 4 weeks or 8 weeks. Similarly, IGF-1 is significantly increased by 24 until 96 hours after PRP, while its activation was decreased after 4 weeks and 8 weeks but with significantly difference compared with the pretest and the control group 8 weeks test. Furthermore, IGF-1 is generated in the liver in response to hGH, is the primary downstream mediator of hGH, and is the most specific marker of supraphysiological hGH exposure [36] [37]. Figure 6. Difference between the case and control group in the concentration of the Growth Factors after 8 weeks. hGH, human growth hormone; IGF-1, insulin-like growth factor-1; FGF-2, basic fibroblast growth factor; VEGF, vascular endothelial growth factor; PDGF, platelet-derived growth factor. Despite that both groups performed the same rehabilitation program, our study reported a significant increase in the growth factors for the control group after 4 and 8 weeks (Table 3, figure 6). However, the values of the case group after 4 weeks for the case group were more advanced than the 8 weeks values of the controlled (Figure 7,8). Therefore, the PRP injection enhanced the concentration of the growth. It is notably that the physical measurements of hamstring force and knee flexion range of motion were not significant at either 4 or 8 weeks. Wallace et al demonstrated that an acute bout of exercise increases total circulating IGF-1 by only about 20% [38] [9]. Figure 7, Difference between the case and control group in (NFROM) Knee flexion range of motion after 8 weeks. Figure 8, Difference between the case and control group in (HF) Hamstring Force after 8 weeks. à à à By comparison, participants in case group who treated with PRP and exercise program. Our study demonstrated a 38% increase in IGF-1 in case group and 9.5% in control group. Relative to baseline, suggesting that PRP treatment activates the hGH-IGF-1 pathway but that a single PRP injection is important to combined with the exercise to maximally stimulate. [39] [9] (Table 3) (Figure 6). We also observed FGF-2 and VEGF also peaked after treatment with PRP.à Fibroblast growth factor contributes to angiogenesis by stimulating the proliferation of endothelial cells to enhance the proliferation of satellite cells, which are the stem cells of mature muscle [40]. Basic fibroblast growth factor may enhance athletic performance by inducing muscle hyper- trophy and increasing oxygen transport. Vascular endothelial growth factor is a powerful stimulator of angiogenesis and could have noteworthy performance-enhancing effects if it entered systemic circulation and exerted its effects in tissues o ther than the site of injury [41]. The potential effects of autologous biological substances to hasten muscle healing were reported in several case reports [34] [42] [43]. Borrione et al [34] noted that athletes with grade 3 muscle strains treated with PRP showed earlier functional improvement and more complete recovery than those treated nonoperatively. Hamid et alà [44] demonstrated that a single PRP injection was effective in accelerating recovery for grade 2. However, the PRP Group achieved full recovery significantly earlier than controls and returned to play after 27 days while control group returned after 43 days. Another approach successfully treated an athlete with a grade 2 semimembranosus muscle injury with a single 3-mL infiltration of platelet-enriched plasma under ultrasound guidance. The athlete was pain free and allowed to train at the preinjury intensity 21 days after treatment [45]. The effect of a preparation rich in growth factors (PRGF) to hasten muscle recovery was reported in a 35-year-old pr ofessional bodybuilder diagnosed with a right adductor longus rupture. The athlete successfully returned to competitive training within 1 week after the third PRGF injection [43]. The effect of PRP in accelerated and associated a hamstring injury was also observed in the current study. The PRP preparation contained a high concentration of several growth factors including TGF-b, FGF-2, and insulin-like growth factor-1, but the amount of platelets and WBCs present was not stated. Additionally, the actual effect of PRP on soft tissue healing is not fully understood,22 our findings supported the possible role of higher growth factors (concentration level) in hastening recovery as postulated by previous researchers [46] [47] [42]. Sanchez et al reported full functional recovery of hamstring and adductor muscle injuries 2 times faster in 20 professional athletes treated with a PRGF [24]. Similar designed study by Rettig et al was investigated the effects of an autologous PRP injection and was retrospective case-control study conducted to determine the effect of the PRP on return time to play after acute hamstring injuries. The study included 10 professional National Football League (NFL) players with acute hamstring injury. The participants were divided equally into PRP and Control groups. Under ultrasound guidance the PRP group patients were injected once with 6 mL of PRP. Both groups were performed the same rehabilitation program. Several differences were identified between the study by Rettig et al and the current study. For instance, the
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